The MARINA project engages citizens, researchers, policy makers, industrial and societal actors in order to improve Responsible Research and Innovation (RRI) around the European marine ecosystem, threatened by   climate change in progress and the intensive human exploitation. The RRI approach is used with all stakeholders in 8 strategic marine Hot Topics issues: marine biotech, sea transportation, deep sea mining (including bio prospecting), marine change caused by climate, renewable energy (wave, wind, tidal), tourism and coastal cities, fishing and aquaculture, pollution caused by human land and sea pressures. Thanks to the on-field experience, MARINA project is strengthening this systematic approach, making it transferable and reproducible for any RRI thematic domain: the project aims to federate all other EU-funded RRI projects, including those not related to marine issues, in order to develop the RRI Roadmap, starting from its best practices and its limitations, and making it useful for many societal challenges. Thanks to MARINA, it will be possible to develop a better alignment between research and innovation and societal needs, transferable also to other important areas such as nanotechnology, biotechnology etc.