Caregiving has traditionally been a female area, both domestically and in the workplace. Due to the nature of influenza, healthcare workers and those in close contact with young children are at a greater risk of exposure to influenza viruses, both seasonal outbreaks and pandemic strains (Zhang et al 2011). Studies have generally shown compliance rates from as low as 10% to 40-50% among healthcare workers, with no clear pattern to ascertain why this is (Tell Me 2012).
Women who are pregnant are more likely to have severe disease and hospitalisation with either seasonal or pandemic influenza, compared to the general population or compared to non-pregnant women of the same age group. During pandemics, the mortality rate for pregnant women is higher than non-pregnant women. However, this is not the case with seasonal influenza unless the strain is particularly severe (WHO 2010).
WHO. 2014. Evaluation of seasonal influenza vaccination policies and coverage in the WHO European Region. Results from the 2008/2009 and
2009/2010 influenza seasons Based on a joint VENICE–ECDC–WHO survey.
People with already existing conditions, such as cardiovascular diseases, diabetes, and pulmonary/respiratory disease, are at greater risk from influenza (Logue et al., 2011). Women are more likely to have diabetes in their lifetime than men, and studies in the US show that women, particularly those in lower socioeconomic groups, receive less adequate diabetes care than men from the same socioeconomic group (WHO, 2010).
Background: The emergence of highly pathogenic avian influenza H5N1 viruses has raised concerns about their pandemic potential. Vaccination is the most effective way of preventing influenza. In this study, we investigated the safety and immunogenicity of an avian H5N2 live attenuated influenza vaccine (LAIV H5N2) in healthy Thai adults and its priming immune responses with an H5N1 inactivated vaccine boost.
WHO. 2011. Bulletin of the World Health Organization. Planning for uncertainty: a European approach to informing responses to the severity of influenza epidemics and pandemics.