Ministers and senior representatives of Member States in the European Region will meet to discuss the numerous public health challenges posed by large-scale movements of refugees and migrants to transit and destination countries. These range from management of communicable and noncommunicable diseases to the impact of large-scale migration on health systems. Given the inter-regional relevance of this topic, ministers from the main countries of origin and of transit of refugees and migrants – in the Eastern Mediterranean and African regions – are also invited.